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Fig. 9 | BioMedical Engineering OnLine

Fig. 9

From: Inhibition of BRD4 inhibits proliferation and promotes apoptosis of psoriatic keratinocytes

Fig. 9

(+)-JQ1 suppressed the MAPK signaling pathway in HaCAT cells induced by TNF-α or IL-17A. A Expression of MAPK pathway-related proteins in HaCAT cells induced by TNF-α was detected by Western blot analysis. ***P < 0.001 vs. Vehicle group. ###P < 0.001 vs. TNF-α 50 ng/ml group. B Expression of MAPK pathway-related proteins in HaCAT cells induced by IL-17A was detected by Western blot analysis. **P < 0.01 and ***P < 0.001 vs. Vehicle group. ###P < 0.001 vs. IL-17A 50 ng/ml group

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