Fig. 4
Lesion volume variation in ex vivo bovine liver after HIFU exposure. At atmospheric pressure (1 bar), the volume of lesions in the 2.0 mg/L and 1.5 mg/L DOC group were 83.28 ± 14.56 mm3 and 76.84 ± 11.07 mm3, respectively. At sub-atmospheric pressure (0.1 bar), the volume of lesions in the 2.0 mg/L, 1.5 mg/L and 1.0 mg/L groups were 20.53 ± 5.54 mm3, 16.01 ± 4.22 mm3 and 0.00 ± 0.00 mm3, respectively. Lesion volume under atmospheric pressure was significantly different from that under sub-atmospheric pressure when DOC was kept the same. *Represents p < 0.05 for significance of difference between the two groups, **represents p > 0.05 for no significance of difference between the two groups