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Fig. 6 | BioMedical Engineering OnLine

Fig. 6

From: Celastrol inhibits the proliferation and angiogenesis of high glucose-induced human retinal endothelial cells

Fig. 6

Celastrol inhibits the angiogenesis of HG-induced hRECs by down-regulating the HIF1α/VEGF signaling pathway. A The branching points in HG-induced hRECs treated with DMOG and celastrol were observed by tube formation assay. B Inverted micrographs of branching points in HG-induced hRECs treated with DMOG and celastrol. C The expression of ICAM-1 in HG-induced hRECs treated with DMOG and celastrol was detected by immunofluorescence assay. **P < 0.01 and ***P < 0.001 vs. NG group. ###P < 0.001 vs. HG group. ∆∆P < 0.01 vs. HG + cela group. Cela: celastrol

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BioMedical Engineering OnLine

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