Fig. 3

Celastrol inhibits the proliferation and invasion of HG-induced hRECs. A The proliferation of hRECs induced with HG and treated with different concentrations of celastrol was detected by MTT assay. B The invasion of hRECs induced with HG and treated with different concentrations of celastrol was observed by Transwell assay. C Optical micrographs of invasion of hRECs induced with HG and treated with different concentrations of celastrol. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. NG group. ^##P < 0.01 and ^###P < 0.001 vs. HG group. ^∆P < 0.05 vs. HG + 0.5 μM cela group. ^$P < 0.05 vs. HG + 1.0 μM cela group. Cela: celastrol