Fig. 4

Comparison of two semi-quantitative assessments of the biodegradation of two types of silk fibroin scaffolds. a A schematic diagram of the measured area of the material in the ultrasound image: the area circled by the yellow line is the measured area. b A schematic diagram of the measured area of the material in the histological examination image: the area circled by the blue line is the measured area. c The cross-sectional areas for two groups of SF scaffolds (A and B) detected by B-mode ultrasound (US)after 3, 7, 14, 28, 56, and 84 days of subcutaneous implantation. d The cross-sectional areas for the two groups of SF scaffolds (A and B) detected by HE staining (HE) after subcutaneous implantation. e The cross-sectional areas of SF-A detected by HE staining (HE) and B-mode ultrasound (US)after 3, 7, 14, 28, 56, and 84 days of subcutaneous implantation. f The cross-sectional areas of SF-B detected by HE staining (HE) and B-mode ultrasound (US)after subcutaneous implantation. (*Statistically significant differences at P ≤ 0.05; ** Statistically significant differences at P ≤ 0.01)