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Table 3 Preliminary panel for miRNA quantification related to prostate cancer development

From: miRNAs as biomarkers for early cancer detection and their application in the development of new diagnostic tools

miRNA

Cellular function

References

let-7 family

Inhibition of cell proliferation, migration, and metastasis

[138,139,140]

miR-17

Promotion of cellular proliferation and tumor angiogenesis

[134]

miR-20a/miR-20b

Regulation of cell proliferation, differentiation, and apoptosis

[134]

miR-100

Inhibition of tumorigenesis, cell proliferation, and signaling

[141]

miR-124

Inhibition of cellular proliferation and migration

[142, 143]

miR-125b

Inhibition of cellular proliferation and induction of metastasis

[144, 145]

miR-132

Inhibition of cellular proliferation and signaling

[146]

miR-141

Inhibition of cellular proliferation and migration

[94, 147]

miR-143

Regulation of apoptotic mechanisms

[148, 149]

miR-145

Inhibition of cellular proliferation, migration and tumor angiogenesis

[150, 151]

miR-148

Regulation of angiogenesis and apoptotic mechanisms

[135]

miR-195

Inhibition of cellular proliferation, cell cycle progression, and metastasis

[152, 153]

miR-200a

Inhibition of cellular proliferation and signaling

[154, 155]

miR-221

Inhibition of cell proliferation and invasion

[156,157,158]

miR-296

Inhibition of cell proliferation and invasion; induction of apoptotic mechanisms

[154, 159, 160]

miR-375

Inhibition of cell proliferation and invasion

[161, 162]

miR-382

Inhibition of cell proliferation, migration, and metastasis

[163]

miR-449

Control of cell proliferation and differentiation

[164, 165]

miR-650

Regulation of pro-inflammatory signals and induction of cell proliferation

[136]

miR-4534

Induction of cell migration and metastasis

[137]