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Table 3 Preliminary panel for miRNA quantification related to prostate cancer development

From: miRNAs as biomarkers for early cancer detection and their application in the development of new diagnostic tools

miRNA Cellular function References
let-7 family Inhibition of cell proliferation, migration, and metastasis [138,139,140]
miR-17 Promotion of cellular proliferation and tumor angiogenesis [134]
miR-20a/miR-20b Regulation of cell proliferation, differentiation, and apoptosis [134]
miR-100 Inhibition of tumorigenesis, cell proliferation, and signaling [141]
miR-124 Inhibition of cellular proliferation and migration [142, 143]
miR-125b Inhibition of cellular proliferation and induction of metastasis [144, 145]
miR-132 Inhibition of cellular proliferation and signaling [146]
miR-141 Inhibition of cellular proliferation and migration [94, 147]
miR-143 Regulation of apoptotic mechanisms [148, 149]
miR-145 Inhibition of cellular proliferation, migration and tumor angiogenesis [150, 151]
miR-148 Regulation of angiogenesis and apoptotic mechanisms [135]
miR-195 Inhibition of cellular proliferation, cell cycle progression, and metastasis [152, 153]
miR-200a Inhibition of cellular proliferation and signaling [154, 155]
miR-221 Inhibition of cell proliferation and invasion [156,157,158]
miR-296 Inhibition of cell proliferation and invasion; induction of apoptotic mechanisms [154, 159, 160]
miR-375 Inhibition of cell proliferation and invasion [161, 162]
miR-382 Inhibition of cell proliferation, migration, and metastasis [163]
miR-449 Control of cell proliferation and differentiation [164, 165]
miR-650 Regulation of pro-inflammatory signals and induction of cell proliferation [136]
miR-4534 Induction of cell migration and metastasis [137]
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