Skip to main content

Table 1 Preliminary panel for miRNA quantification related to breast cancer development

From: miRNAs as biomarkers for early cancer detection and their application in the development of new diagnostic tools

miRNA

Cellular function

References

let-7 family

Inhibition of cell proliferation, migration, and metastasis

[46, 83]

miR-1

Inhibition of tumor growth and metastasis

[97, 171]

miR-21

Promotion of cellular proliferation and tumor angiogenesis

[46, 83, 84]

miR-26a

Promotion of cell proliferation and differentiation in several tissues

[85, 86]

miR-100

Inhibition of tumorigenesis, cell proliferation and signaling

[98, 99]

miR-125b

Inhibition of cellular proliferation and induction of metastasis

[83, 100, 172]

miR-126

Inhibition of cell invasion by ADAM9 downregulation

[103, 104]

miR-145

Inhibition of cellular proliferation, migration, and tumor angiogenesis

[83, 105, 106]

miR-155

Promotion of cellular proliferation and tumor angiogenesis

[83, 87]

miR-195

Regulation of apoptosis and inhibition of tumor invasion

[111]

miR-199a

Inhibition of tumor invasion and metastasis

[84]

miR-200c

Regulation of apoptosis and metastasis

[29]

miR-203

Inhibition of tumorigenesis, cell proliferation, and signaling

[173]

miR-210

Response to hypoxia and stress conditions

[107, 174, 175]

miR-221/miR-222

Promotion of cellular migration and proliferation

[88,89,90]

miR-298

Response to hypoxia and control of cell proliferation

[108]

miR-331

Regulation cell proliferation, apoptosis, and inhibition of tumor invasion

[111]

miR-335

Regulation of BRCA1 expression, inhibition of cellular proliferation and migration

[109, 110]

miR-340

Regulation cell proliferation and inhibition of tumor invasion

[176]

miR-495

Promotion of cellular migration, proliferation, and response to hypoxia

[91]