Fig. 2

Knockdown of miR-153 decreased serum levels of LDH, CK-MB, AST, and BNP. Serum samples from rats as indicated in Fig. 1 were subjected to ELISA analysis of LDH (a), CK-MB (b), AST (c), and BNP (d). n = 8 for each group. Experiments have repeated for three times independently. Data are presented as mean ± SD. *p < 0.05, **p < 0.01, and ***p < 0.001 compared to sham group. ^#p < 0.05 compared to IR group. LDH lactate dehydrogenase, CK-MB creatine kinase-MB, AST aspartate aminotransferase, BNP brain natriuretic peptide