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Table 8 Diagnostic accuracy (mean and 95% confidence interval) of the eRIC and fractional-order parameters in the detection of respiratory alterations in patients with work-related asthma

From: Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

  AUC Se (%) Sp (%) Cut-off
eRIC
 R 0.514
0.384–0.643
74.2
55.4–88.1
41.9
24.5–60.9
≤ 2.87
 Rt 0.703
0.574–0.813
41.9
24.5–60.9
96.7
83.3–99.9
> 3.68
 Rp 0.838
0.734–0.942
67.7
48.6–83.3
96.8
83.3–99.9
> 0.80
 I 0.746
0.619–0.848
64.5
45.4–80.8
80.6
62.5–92.5
≤ 0.007
 C 0.747
0.621–0.849
58.0
39.1–75.5
93.5
78.6–99.2
≤ 0.01
FrOr
 G 0.729
0.602 to 0.856
74.19
55.4–88.1
58.06
39.1–75.5
> 13.53
 H 0.881
0.785–0.978
83.87
66.3–94.5
90.33
74.2–98.0
< 23.12
 η 0.970
0.915–1.000
96.77
83.3–99.9
96.77
83.3–99.9
> 0.658
  1. Values considered adequate are described in italic
  2. AUC: area under the receiver operator curve; Se: sensibility; Sp: specificity; eRIC: extended resistance–inertance–compliance model; FrOr: fractional order; R: central airway resistance; Rp: peripheral resistance; Rt: total resistance; I: pulmonary inertance; C: alveolar compliance; G: damping factor; H: elastance; η: hysteresivity coefficient