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Table 7 Diagnostic accuracy (mean and 95% confidence interval) of the traditional FOT parameters in the diagnostic of respiratory abnormalities in patients with work-related asthma

From: Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

  AUC Se (%) Sp (%) Cut-off
R0 0.687
0.556–0.799
45.1
27.3–64.0
93.5
78.6–99.2
> 3.53
Rm 0.634
0.502–0.753
35.4
19.2–54.6
96.7
83.3–99.9
> 3.54
R4 0.673
0.542–0.787
38.7
21.8–57.8
96.7
83.3–99.9
> 3.70
R12 0.635
0.503–0.753
38.7
21.8–57.8
87.1
70.2–96.4
> 3.13
R20 0.513
0.383–0.642
100
88.8–100.0
12.9
3.6–29.8
> 1.49
S 0.840
0.745–0.934
67.7
48.6–83.3
80.6
62.5–92.5
≤ − 23.3
R4 − R20 0.795
0.673–0.887
80.6
62.5–92.5
64.5
45.4–80.8
> 0.16
Xm 0.826
0.724–0.929
67.7
48.6–83.3
87.1
70.2–96.4
≤ − 0.03
Fr 0.929
0.835–0.979
74.2
55.4–88.1
100
88.8–100.0
> 14.7
Cdyn 0.695
0.565–0.806
48.3
30.2–66.9
90.3
74.2–98.0
≤ 12.41
Axt 0.875
0.767–0.945
70.9
52.0–85.8
96.7
83.3–99.9
> 13.56
Axi 0.819
0.701–0.906
80.6
62.5–92.5
67.7
48.6–83.3
> 7.08
Z4 0.690
0.558–0.822
48.3
30.2–66.9
87.1
70.2–96.4
> 4.54
  1. Values considered adequate are described in italic
  2. AUC: area under the receiver operating curve; Se: sensitivity; Sp: specificity; R0: intercept resistance; Rm: mean resistance; S: slope of the resistive values; R4: resistance in 4 Hz; R12: resistance in 12 Hz; R20: resistance in 20 Hz; Xm: mean reactance; Fr: resonance frequency; Cdyn: dynamic compliance; Axt: area under the reactance curve using the approximation by a triangle; Axi: area under the reactance curve using the integral based on the trapezoidal rule; Z4: impedance modulus in 4 Hz. eRIC: extended resistance–inertance–compliance model; FrOr: fractional order; R: central airway resistance; Rp: peripheral resistance; Rt: total resistance; I: pulmonary inertance; C: alveolar compliance; G: damping factor; H: elastance; η: hysteresivity coefficient