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Table 6 Association among traditional, eRIC and fractional-order parameters and plethysmographic analysis

From: Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

  VC (L) IC (L) ERV (L) TV (L) RV/TLC FRC (L) RV (L) TLC (L) TGV (L) Raw SGaw
Resistive
 R0 − 0.36
< 0.05
− 0.41
< 0.03
− 0.09
ns
− 0.34
ns
0.05
ns
− 0.20
ns
0.03
ns
− 0.31
ns
− 0.20
ns
0.35
ns
− 0.30
ns
 Rm − 0.39
< 0.03
− 0.41
< 0.02
− 0.14
ns
− 0.34
ns
0.02
ns
− 0.25
ns
− 0.20
ns
− 0.37
< 0.04
− 0.23
ns
0.21
ns
− 0.17
ns
 S 0.22
ns
0.30
Ns
− 0.0005
ns
0.25
ns
− 0.09
ns
0.06
ns
− 0.004
ns
0.09
ns
0.09
ns
− 0.57
0.0007
0.51
< 0.003
 R4 − 0.37
< 0.04
− 0.43
< 0.02
− 0.08
ns
− 0.34
ns
0.06
ns
− 0.19
ns
− 0.15
ns
− 0.32
ns
− 0.18
ns
0.28
ns
− 0.28
ns
 R12 − 0.39
< 0.03
− 0.41
< 0.02
− 0.12
ns
− 0.32
ns
0.01
ns
− 0.25
ns
− 0.19
ns
− 0.37
ns
− 0.23
ns
0.21
ns
− 0.20
ns
 R20 − 0.43
< 0.02
− 0.42
< 0.02
− 0.18
ns
− 0.34
ns
0.008
ns
− 0.28
ns
− 0.24
ns
− 0.44
< 0.02
− 0.24
ns
− 0.02
ns
0.03
ns
 R4 − R20 − 0.11
ns
− 0.23
ns
0.08
ns
− 0.16
ns
0.1
ns
0.02
ns
0.03
ns
− 0.008
ns
− 0.01
ns
0.52
< 0.003
− 0.54
< 0.002
Reactive
 Xm 0.26
ns
0.29
ns
0.03
ns
0.22
ns
− 0.13
ns
0.006
ns
− 0.01
ns
0.09
ns
0.02
ns
− 0.58
0.0005
0.49
< 0.006
 Fr − 0.38
< 0.04
− 0.39
< 0.03
− 0.06
ns
− 0.30
ns
0.30
ns
0.18
ns
0.10
ns
− 0.04
ns
0.13
ns
0.40
< 0.03
− 0.38
< 0.04
 Cdyn 0.40
< 0.03
0.38
< 0.04
0.22
ns
0.30
ns
0.08
ns
0.37
< 0.05
0.20
ns
0.36
< 0.05
0.36
< 0.05
− 0.30
ns
0.24
ns
 Axt − 0.25
ns
− 0.28
ns
− 0.07
ns
− 0.24
ns
0.07
ns
− 0.09
ns
− 0.04
ns
− 0.15
ns
− 0.09
ns
0.56
0.0008
− 0.41
< 0.03
 Axi − 0.22
ns
− 0.27
ns
− 0.05
ns
− 0.23
ns
0.05
ns
− 0.09
ns
− 0.04
ns
− 0.13
ns
− 0.09
ns
0.59
0.0004
− 0.46
< 0.008
 Z4 − 0.32
ns
− 0.36
< 0.05
− 0.11
ns
− 0.30
ns
0.02
ns
− 0.21
ns
− 0.13
ns
− 0.27
ns
− 0.20
ns
0.44
< 0.02
− 0.33
< 0.07
eRIC
 R − 0.37
< 0.04
− 0.35
ns
− 0.20
ns
− 0.30
ns
− 0.05
ns
− 0.32
ns
− 0.30
ns
− 0.46
< 0.008
− 0.28
ns
− 0.20
ns
0.16
ns
 Rp − 0.21
ns
− 0.33
ns
0.09
ns
− 0.23
ns
0.10
ns
− 0.01
ns
− 0.009
ns
− 0.09
ns
− 0.03
ns
0.50
< 0.004
− 0.48
< 0.007
 Rt − 0.38
< 0.04
− 0.46
< 0.01
− 0.04
ns
− 0.35
< 0.05
0.04
ns
− 0.19
ns
− 0.18
ns
− 0.34
ns
− 0.18
ns
0.27
ns
− 0.27
ns
 I 0.10
ns
0.09
ns
− 0.01
ns
0.06
ns
− 0.25
ns
− 0.27
ns
− 0.14
ns
− 0.13
ns
− 0.25
ns
− 0.41
< 0.02
0.35
< 0.05
 C 0.30
ns
0.32
ns
0.19
< 0.04
0.21
ns
0.13
ns
0.39
< 0.03
0.20
ns
0.32
ns
0.45
< 0.02
− 0.41
< 0.03
0.37
< 0.04
FrOr
 G − 0.15
ns
− 0.16
ns
− 0.16
ns
− 0.20
ns
− 0.15
ns
− 0.34
ns
− 0.22
ns
− 0.25
ns
− 0.32
ns
0.53
< 0.003
− 0.31
ns
 H − 0.31
ns
− 0.31
ns
− 0.14
ns
− 0.27
ns
0.07
ns
− 0.16
ns
− 0.07
ns
− 0.25
ns
− 0.13
ns
0.36
< 0.05
− 0.16
ns
 η 0.13
ns
0.15
ns
− 0.16
ns
− 0.05
ns
− 0.19
ns
− 0.16
ns
− 0.08
ns
0.03
ns
− 0.24
ns
0.53
< 0.003
− 0.34
ns
  1. Significance was analyzed after Bonferroni correction. The significant associations are described in italic
  2. FEV1: forced expiratory volume in the first second; FVC: forced vital capacity; FEF: forced expiratory flow between 25 and 75% of the FVC; %: percentage of the predicted values; R0: intercept resistance; Rm: mean resistance; S: slope of the resistive values; R4: resistance in 4 Hz; R12: resistance in 12 Hz; R20: resistance in 20 Hz; Xm: mean reactance; Fr: resonance frequency; Cdyn: dynamic compliance; Axt: area under the reactance curve using the approximation by a triangle; Axi: area under the reactance curve using the integral based on the trapezoidal rule; Z4: impedance modulus in 4 Hz; eRIC: extended resistance–inertance–compliance model; FrOr: fractional order; R: central airway resistance; Rp: peripheral resistance; Rt: total resistance; I: pulmonary inertance; C: alveolar compliance; G: damping factor; H: elastance; η: hysteresivity coefficient