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Table 3 Oscillometric characteristics of control individuals and patients with work-related asthma and the effect of bronchodilator use

From: Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

 

Control (n = 31)

Work-related asthma before BD (n = 31)

Work-related asthma post BD (n = 31)

Resistive parameters

 R0 (cmH2O/L/s)

2.7 ± 0.7

3.9 ± 1.8*

2.8 ± 1.1‡‡‡

 Rm (cmH2O/L/s)

2.6 ± 0.6

3.3 ± 1.3

2.5 ± 0.8‡‡‡

 S (cmH2O/L/s2)

− 8.9 ± 18.7

− 66.0 ± 65****

− 32.7 ± 43.5‡‡‡

 R4 (cmH2O/L/s)

2.6 ± 0.7

3.6 ± 1.5*

2.6 ± 0.9‡‡‡

 R12 (cmH2O/L/s)

2.4 ± 0.6

3.0 ± 1.1

2.3 ± 0.8‡‡‡

 R20 (cmH2O/L/s)

2.6 ± 0.7

2.8 ± 1.1

2.2 ± 0.8‡‡‡

R4− R20 (cmH2O/L/s)

0.03 ± 0.3

0.7 ± 0.9****

0.3 ± 0.5‡‡

Reactive parameters

 Xm (cmH2O/L/s)

0.4 ± 0.3

− 0.4 ± 0.9****

− 0.07 ± 0.6‡‡‡

 Fr (Hz)

11.3 ± 1.5

20.0 ± 6.6****

17.2 ± 6.4

 Cdyn (mL/cmH2O)

18.8 ± 6.3

14.4 ± 5.8**

19.4 ± 6.1‡‡‡

 Axt (cmH2O/L)

8.7 ± 3.5

31.4 ± 30.1****

19.1 ± 22.0‡‡‡

 Axi (cmH2O/L)

6.2 ± 2.6

20.4 ± 20.4****

11.9 ± 12.6‡‡‡

 Z4 (cmH2O/L/s)

3.5 ± 0.9

5.0 ± 2.3*

3.6 ± 1.5‡‡‡

  1. Data are mean ± SD
  2. R0: intercept resistance; Rm: mean resistance; S: slope of the resistive values; R4: resistance in 4 Hz; R12: resistance in 12 Hz; R20: resistance in 20 Hz; Xm: mean reactance; Fr: resonance frequency; Cdyn: dynamic compliance; Axt: area under the reactance curve using the approximation by a triangle; Axi: area under the reactance curve using the integral based on the trapezoidal rule; Z4: impedance modulus in 4 Hz
  3. *p < 0.05 related to control group
  4. **p < 0.01 related to control group
  5. ***p < 0.001 related to control group
  6. ****p < 0.0001 related to control group
  7. p < 0.01 related to pre-BD
  8. ‡‡p < 0.001 related to pre-BD
  9. ‡‡‡p < 0.0001 related to pre-BD