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Table 2 Spirometric and plethysmographic characteristics of control individuals and patients with work-related asthma

From: Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

  Control (n = 31) Work-related asthma before BD (n = 31) Work-related asthma post BD (n = 31)
Spirometry
 FEV1 (L) 2.8 ± 0.7 2.3 ± 0.6** 2.5 ± 0.7‡‡
 FEV1 (%) 93.1 ± 15.0 75.6 ± 19.2*** 81.3 ± 17.4‡‡‡‡
 FVC (L) 3.5 ± 0.8 3.1 ± 0.7 3.3 ± 0.8
 FVC (%) 95.3 ± 15.1 84.1 ± 15.0** 86.6 ± 14.0‡‡
 FEV1/FVC 79.9 ± 6.7 72.6 ± 11.7* 76.4 ± 10.2
 FEF 25–75% 2.9 ± 1.1 2.0 ± 1.1** 2.4 ± 1.2
 FEF/CVF 0.7 ± 0.2 0.6 ± 0.3 0.7 ± 0.3
 EPF 7.1 ± 1.8 5.5 ± 2.0** 5.7 ± 2.2
Plethysmography
 VC (L) 3.73 ± 0.6 2.95 ± 0.7*** 3.16 ± 0.6
 IC (L) 2.45 ± 0.6 2.69 ± 0.6* 2.93 ± 0.6
 ERV (L) 1.31 ± 0.08 0.33 ± 0.2*** 0.26 ± 0.2
 TLC (L) 5.48 ± 0.9 5.27 ± 1.1 5.14 ± 1.3
 TV (L) 0.86 ± 0.3 0.87 ± 0.2
 RV (L) 1.7 ± 0.3 2.3 ± 0.8*** 2.0 ± 0.9
 RV/TLC 31.11 ± 3.1 43.8 ± 12.9*** 39 ± 11.6
 FRC 3.02 ± 0.35 2.86 ± 1.2 2.3 ± 1.0
 TGV 3.2 ± 1.3 2.7 ± 1.26
 Raw 1.38 ± 0.09 5.8 ± 5.2*** 3.7 ± 3.1‡‡
 SGaw 0.24 ± 0.02 0.12 ± 0.09*** 0.16 ± 0.1
  1. Data are mean ± SD; % = percentage of the predicted values
  2. FEV1: forced expiratory volume in the first second, FVC: forced vital capacity, FEF: forced expiratory flow between 25 and 75% of the FVC, %: percentage of the predicted values, EPF: expiratory peak flow, TLC: total lung capacity, FRC: functional residual capacity, ERV: expiratory reserve volume, RV: residual volume, Raw: airway resistance, TGV: thoracic gas volume, SGaw: specific airway resistance
  3. *p < 0.05 related to control group
  4. **p < 0.01 related to control group
  5. ***p < 0.001 related to control group
  6. p < 0.05 related to pre-BD
  7. ‡‡p < 0.01 related to pre-BD