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Table 10 Diagnostic accuracy (mean and 95% confidence interval) of the eRIC and fractional-order parameters in the detection of respiratory effects of bronchodilator use in patients with work-related asthma

From: Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

  AUC Se (%) Sp (%) Cut-off
eRIC
 R 0.678
0.544–0.813
67.7
48.6–83.3
67.7
48.6–83.3
≤ 2.1
 Rt 0.664
0.529–0.799
93.6
78.6–99.2
32.2
16.7–51.4
> 2.59
 Rp 0.546
0.400–0.693
29.0
14.2–48.0
96.7
83.3–99.9
> 1.81
 I 0.518
0.372–0.663
29.0
14.2–48.0
83.8
66.3–94.5
≤ 0.003
 C 0.651
0.513–0.790
58.0
39.1–75.5
77.4
58.9–90.4
≤ 0.01
FrOr
 G 0.660
0.528–0.775
61.29
42.2–78.2
64.52
45.4–80.8
≤ 14.65
 H 0.645
0.513–0.763
74.19
55.4–88.1
61.29
42.2–78.2
≤ 16.81
 η 0.505
0.375–0.634
58.06
39.1–75.5
58.06
39.1–75.5
≤ 0.93
  1. AUC: area under the receiver operator curve; Se: sensibility; Sp: specificity; eRIC: extended resistance–inertance–compliance model; FrOr: fractional order; R: central airway resistance; Rp: peripheral resistance; Rt: total resistance; I: pulmonary inertance; C: alveolar compliance; G: damping factor; H: elastance; η: hysteresivity coefficient