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Table 10 Diagnostic accuracy (mean and 95% confidence interval) of the eRIC and fractional-order parameters in the detection of respiratory effects of bronchodilator use in patients with work-related asthma

From: Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

 

AUC

Se (%)

Sp (%)

Cut-off

eRIC

 R

0.678

0.544–0.813

67.7

48.6–83.3

67.7

48.6–83.3

≤ 2.1

 Rt

0.664

0.529–0.799

93.6

78.6–99.2

32.2

16.7–51.4

> 2.59

 Rp

0.546

0.400–0.693

29.0

14.2–48.0

96.7

83.3–99.9

> 1.81

 I

0.518

0.372–0.663

29.0

14.2–48.0

83.8

66.3–94.5

≤ 0.003

 C

0.651

0.513–0.790

58.0

39.1–75.5

77.4

58.9–90.4

≤ 0.01

FrOr

 G

0.660

0.528–0.775

61.29

42.2–78.2

64.52

45.4–80.8

≤ 14.65

 H

0.645

0.513–0.763

74.19

55.4–88.1

61.29

42.2–78.2

≤ 16.81

 η

0.505

0.375–0.634

58.06

39.1–75.5

58.06

39.1–75.5

≤ 0.93

  1. AUC: area under the receiver operator curve; Se: sensibility; Sp: specificity; eRIC: extended resistance–inertance–compliance model; FrOr: fractional order; R: central airway resistance; Rp: peripheral resistance; Rt: total resistance; I: pulmonary inertance; C: alveolar compliance; G: damping factor; H: elastance; η: hysteresivity coefficient