Fig. 3
From: Endothelial shear stress enhancements: a potential solution for critically ill Covid-19 patients
A schema representing the mechanism of the alternating pulsations of the thoracic (T2) and abdominal (T1) compartments of the CFR device. The upper panel shows the CFR in an inspiration phase. The lower panel shows the CFR in an expiration phase. C = covering endothelial layer shearing zone; C-1 = thoracic cage; C-2 = mediastinal shearing mass; C-3 = pulmonary parenchyma, C-4 = diaphragmatic pump; C-5 = hepatosplanchnic shearing mass