Fig. 1
From: Endothelial shear stress enhancements: a potential solution for critically ill Covid-19 patients
Biophysics of cardiopulmonary circulatory driving forces. I Right-heart circuit main remodeling zones: Z1, systemic veins; Z2, right ventricle; Z3, septum; Z4, infundibulum; Z5, pulmonary artery [10]. II Respiratory pump, a low-pressure, momentarily hydraulic circuit that compresses two types of fluids: Newtonian (air) and non-Newtonian (blood), in an accordion-like manner, creating ESS. III Left-heart circuit main remodeling zones: Z1, left ventricle; Z2, Aorta and Valsalva. IV Mechanical ventilator. V: CFR device [23]