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Fig. 4 | BioMedical Engineering OnLine

Fig. 4

From: Investigation of safety for electrochemotherapy and irreversible electroporation ablation therapies in patients with cardiac pacemakers

Fig. 4

The impact of the presence of metallic-encased pacemaker during IRE ablation of tumor. Images show computed results at the end of pulse delivery for one of six active electrode pairs in the simulated procedure. The simulated pulse protocol was 90 × 90 μs pulses delivered at 1 Hz with a pause of 3 s after each set of 10 pulses. Applied voltage to distance ratio was 1500 V/cm. a–c Electric field distribution in target tissue; d–f Temperature in the target tissue. In the control model, the pacemaker is not present in the simulation. In the no-contact model pacemaker is positioned 5 mm from the rightmost electrode. In the contact model, the pacemaker is in conductive contact with the rightmost electrode. The top and side views correspond with the model geometry shown in Fig. 6b

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