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Fig. 1 | BioMedical Engineering OnLine

Fig. 1

From: The effects of pressure- versus volume-controlled ventilation on ventilator work of breathing

Fig. 1

Resistive MW of the ventilator (cmH2O.L) assuming different flow waveforms (square, sinusoidal, and decelerating) for both normal subjects (left column) and COPD patients (right column) with RR = 15/min and different I:E ratios under different tidal volumes; a, d) VT = 0.5 L, b, e) VT = 1 L, c, f) VT = 2 L; increasing I:E ratio in the same RR would decrease MW for all flow profiles. For a fixed I:E ratio, the square profile has the smallest MW for all VT = 0.5 L (see blue bars) while the largest MW is achieved by sinusoidal or decelerating depending on I:E ratio. Resistive MW in COPD patients is about two times higher than that in normals

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