Elaboration of a multimodal MRI-based radiomics signature for the preoperative prediction of the histological subtype in patients with non-small-cell lung cancer

Table 1 Baseline demographics of the patients involved in this research

Characteristics	Training cohort (n = 100)	Validation cohort (n = 48)	p value
Age, years			0.055
Median [range]	58 [20, 76]	61 [42, 83]
Sex, no. (%)			0.220
Male	79/100 (79%)	33/48 (68.75%)
Female	21/100 (21%)	15/48 (31.25%)
Smoking, no. (%)			0.707
Yes	70/100 (70%)	32/48 (66.7%)
No	30/100 (30%)	16/48 (33.3%)
Side, no. (%)			0.389
Upper left lobe	34/100 (34%)	12/48 (25%)
Lower left lobe	14/100 (14%)	8/48 (16.7%)
Upper right lobe	22/100 (22%)	12/48 (25%)
Middle right lobe	4/100 (4%)	2/48 (4.2%)
Lower right lobe	26/100 (26%)	14/48 (29.1%)
Location, no. (%)			0.216
Peripheral	63/100 (63%)	25/48 (52.1%)
Central	37/100 (37%)	23/48 (47.9%)
LD, mm^a			0.230
Median [range]	54 [10, 115]	43.5 [15, 100]
LPD, mm^a			0.838
Median [range]	36.5 [8, 77]	35 [11, 90]
CEA, (ng/ml)^a			0.380
Median [range]	4.7 [0.486, 1135]	7.11 [1.19, 646.4]
Histological subtype, no. (%)			0.164
Squamous cell carcinoma	50/100 (50%)	18/48 (37.5%)
Adenocarcinoma	50/100 (50%)	30/48 (62.5%)

^aLD, LPD and CEA indicate the longest diameter, the longest perpendicular diameter, and carcinoembryonic antigen, respectively

ISSN: 1475-925X