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Fig. 4 | BioMedical Engineering OnLine

Fig. 4

From: Selective modulation of neuronal firing by pulse stimulations with different frequencies in rat hippocampus

Fig. 4

Changes of firing rates of the two types of neurons induced by stimulation trains (0.5 s) with various pulse frequencies. af Neuronal firing rates for stimulation frequencies of 10, 20, 50, 100, 200 and 400 Hz, respectively. Left: dynamic curves of the firing rates. The shadows denote the stimulation periods. The solid and dashed curves denote the means and standard deviations, respectively. Middle: comparisons of the mean firing rates between the periods before and during stimulation with scatter plots (in logarithmic coordinate axes) for each neuron and bar graphs for the two types of neurons. **P < 0.01, paired t tests between firing rates before and during stimulations. Right: comparisons of the mean firing rates between the periods before and after stimulation. ##P < 0.01, t tests between firing rates of interneurons and pyramidal cells. n = 12 for interneurons (Int) and n = 27 for pyramidal cells (Pyr)

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