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Table 6 Different commercial forms of collagen materials and their properties solubility under different conditions, their estimated molecular weight and its distribution, helical degree and estimated crosslinking content

From: Processing of collagen based biomaterials and the resulting materials properties

Material Example Possible supplier Solubility (aqueous saline buffer 0.1% < 40 °C) Solubility (aqueous saline buffer 0.1% > 40 °C) Solubility (acetic acid 0.1 M < 15 °C) Average molecular weight Molecular weight distribution Crosslinking content Triple helix content native (+) denatured (−)
HMDI crosslinked porcine skin Permacol Covidien ++++ +
Lyophilised porcine skin Xenoderm MBP ++ +
Lyophilised sponge from porcine skin dispersion Surgicoll MBP ++ +
Convection dried sheet from equine tendon dispersion Resodont Resorba ++ +
Denatured powder from skin collagen Thermoplastic collagen FILK ± Several millions ++++ +
Acidic extract (cold) from calf skin Soluble collagen Symatese + + + 270 kDa + ± +
Aqueous extract (hot) from limed skin or bone Gelatine Gelita ± + ± Ca. 50–150 kDa +++
Enzymatically treated extract (hot) from skin or bone Collagen hydrolysate Gelita + + + Ca. 5–20 kDa ++