Table 6 Different commercial forms of collagen materials and their properties solubility under different conditions, their estimated molecular weight and its distribution, helical degree and estimated crosslinking content
From: Processing of collagen based biomaterials and the resulting materials properties
Material | Example | Possible supplier | Solubility (aqueous saline buffer 0.1% < 40 °C) | Solubility (aqueous saline buffer 0.1% > 40 °C) | Solubility (acetic acid 0.1 M < 15 °C) | Average molecular weight | Molecular weight distribution | Crosslinking content | Triple helix content native (+) denatured (−) |
|---|---|---|---|---|---|---|---|---|---|
HMDI crosslinked porcine skin | Permacol | Covidien | − | − | − | ∞ | ∞ | ++++ | + |
Lyophilised porcine skin | Xenoderm | MBP | − | − | − | ∞ | ∞ | ++ | + |
Lyophilised sponge from porcine skin dispersion | Surgicoll | MBP | − | − | − | ∞ | ∞ | ++ | + |
Convection dried sheet from equine tendon dispersion | Resodont | Resorba | − | − | − | ∞ | ∞ | ++ | + |
Denatured powder from skin collagen | Thermoplastic collagen | FILK | − | ± | − | Several millions | ++++ | + | − |
Acidic extract (cold) from calf skin | Soluble collagen | Symatese | + | + | + | 270 kDa | + | ± | + |
Aqueous extract (hot) from limed skin or bone | Gelatine | Gelita | ± | + | ± | Ca. 50–150 kDa | +++ | − | − |
Enzymatically treated extract (hot) from skin or bone | Collagen hydrolysate | Gelita | + | + | + | Ca. 5–20 kDa | ++ | − | − |