Fig. 4

Parameter space (top) and strain pattern (bottom) representations of cohorts (yellow) generated by five (1–5) selected parent strain patterns (orange) for the global HF pathology. The cohorts were generated using a threshold of 0.02. Cohorts 1 and 4 have a small overlap region in the parameter space. Each cohort has a different shape and size. In the strain pattern representation, all 1025 simulated strain patterns from the HF pathology are shown as a light coloured background. The shapes of all cohorts in the parameter space are shown for all global pathologies in Additional files 1, 2, 3, 4