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Fig. 6 | BioMedical Engineering OnLine

Fig. 6

From: Surface functionalization of TiO2 nanotubes with minocycline and its in vitro biological effects on Schwann cells

Fig. 6

Gene expression level of (A–C) NGF and (D–F) GDNF in Schwann cells at (A, D) 1 day, (B, E) 4 days and (C, F) 7 days by real-time PCR (mean ± SD, n = 6).The mRNA expression of NGF and GNDF were up-regulated since 1 day in groups with minocycline incorporation. TNT + 20MC dramatically and continuously increased from 1 to 7 days. NGF expression in TNT + 20MC at 7 days was approximate 2.5-fold and 2-fold that of pure titanium and TNT group, respectively. GDNF expression in TNT + 20MC at 7 days was approximate over 2-fold and 1.5 fold that of pure titanium and TNT group, respectively. Values with dissimilar letters are significantly different from each other (p < 0.05)

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