Skip to main content

Table 1 Inhibition of cardiac ion currents in the presence of amiodarone

From: Effects of amiodarone on short QT syndrome variant 3 in human ventricles: a simulation study

Drug Amiodarone
Current I Kr I Na I NaK I CaL I NaCa I Ks
IC50 (µM) 2.80 4.84 15.60 5.80 3.30 3.84
nH 0.91 0.76 1.00 1.00 1.00 0.63
Source [27] [28] [29] [30] [31] [32]
  1. Data used in this study showing inhibition of ion currents in the presence of amiodarone. Half-maximal inhibitory concentration (IC50) and Hill coefficient (nH) values for amiodarone extracted from literatures