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Table 1 Inhibition of cardiac ion currents in the presence of amiodarone

From: Effects of amiodarone on short QT syndrome variant 3 in human ventricles: a simulation study

Drug

Amiodarone

Current

I Kr

I Na

I NaK

I CaL

I NaCa

I Ks

IC50 (µM)

2.80

4.84

15.60

5.80

3.30

3.84

nH

0.91

0.76

1.00

1.00

1.00

0.63

Source

[27]

[28]

[29]

[30]

[31]

[32]

  1. Data used in this study showing inhibition of ion currents in the presence of amiodarone. Half-maximal inhibitory concentration (IC50) and Hill coefficient (nH) values for amiodarone extracted from literatures
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