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Fig. 2 | BioMedical Engineering OnLine

Fig. 2

From: Effects of amiodarone on short QT syndrome variant 3 in human ventricles: a simulation study

Fig. 2

Simulated current–voltage (IV) relationships. ac Currents traces for WT, WT-D172N and D172N I K1 elicited by 400 ms depolarizing voltage steps from −120 to +20 mV and from a holding potential of −60 mV. df Current–voltage relationships. The current amplitude of the WT-D172N and D172N mutant conditions is significantly larger than that of the WT condition

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