Table 2 Values of the steady states in models with or without drug application (drug dose 140,000 molecules)
Model | Drug | G | R | A |
|---|---|---|---|---|
Gene | mRNA | Protein | ||
Without feedback | − | 1.0000 | 333.33 | 160,087 |
Without feedback | + | 1.0000 | 333.33 | 53,060 |
Negative feedback | − | 0.9996 | 333.19 | 160,020 |
Negative feedback | + | 1.3346 | 444.85 | 70,811 |
Positive feedback | − | 1.0053 | 335.09 | 160,930 |
Positive feedback | + | 0.3656 | 121.87 | 19,399 |