Fig. 6From: Rational confederation of genes and diseases: NGS interpretation via GeneCards, MalaCards and VarElectDisease SuperPaths are created by applying the PathCards biological pathway clustering algorithm to disease pathways, as explained in the text. Bottom left—the collection of all disease SuperPaths; Center—a specific disease SuperPath that appears to strongly represent Gaucher disease types, and diseases with related etiology. Each rectangular edge is a disease pathway, shown at the top right as an oval circumference, containing the disease genes that constitute the disease pathway. A connecting red line is an edge in the disease SuperPath, defined by gene sharing between the two disease pathways (genes shared by two ovals); The disease SuperPaths provide novel (indirect) disease–disease association, whereby two disease pathways that share no associated genes are linked to each other via the fact that there is a third disease pathway that shares gene with both (see text)Back to article page