Skip to main content
Fig. 5 | BioMedical Engineering OnLine

Fig. 5

From: Rational confederation of genes and diseases: NGS interpretation via GeneCards, MalaCards and VarElect

Fig. 5

a Genes within a biological pathway allow for inference of disease relation to other pathway members (guilt by association). The same role can be played by genes associated with a disease, defined here as a “disease pathway”. b Genes within a disease pathway need not show significant overlap to canonical biological pathways. It was found that only 11.4 ± 5.5% of gene pairs in disease pathways also belonged to the same SuperPath. Therefore, disease pathways entail a new point of view for functional gene grouping

Back to article page