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Fig. 3 | BioMedical Engineering OnLine

Fig. 3

From: Preparation and characterization of small-diameter decellularized scaffolds for vascular tissue engineering in an animal model

Fig. 3

Biocompatibility of decellularized blood vessel scaffolds in vivo. H&E staining showing host cell infiltration in decellularized scaffolds from rats at various time points following subcutaneous implantation compared to fresh vascular controls: day 7 (16); day 14 (712); day 28 (1318); and day 56 (1924). The images show progressive degradation and a decrease in inflammatory infiltration in the experimental scaffolds over time. In contrast, the extent of inflammatory infiltration in the control sample remains high throughout, with a clear boundary separating the scaffolds from the receptor tissue. At day 56, there is almost no evidence of the scaffold in the experimental groups. The blue arrow indicates the scaffold position; the suture points are identified by a dark grey point (magnification, ×100)

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