Table 3 Diagnostic performance of FFRCTA, FFRSS and CCTA on a per-vessel and -patient basis
Measure | Per-vessel | Per-patient | ||||
|---|---|---|---|---|---|---|
FFRCTA ≤0.8 (95% CI) | FFRSS ≤0.8 (95% CI) | CCTA stenosis >50% (95% CI) | FFRCTA ≤0.8 (95% CI) | FFRSS ≤0.8 (95% CI) | CCTA stenosis >50% (95% CI) | |
Accuracy | 80.6 (64.9–90.2) | 75.0 (58.9–86.3) | 61.6 (44.8–75.2) | 79.3 (61.6–90.1) | 72.4 (54.3–85.3) | 62.1 (44.0–77.3) |
Sensitivity | 94.1 (71.3–99.9) | 94.1 (73.0–98.9) | 88.2 (63.6–98.5) | 93.7 (69.8–99.8) | 93.7 (71.7–98.9) | 87.5 (61.7–98.4) |
Specificity | 68.4 (43.4–87.4) | 57.9 (36.3–76.9) | 36.8 (16.3–61.6) | 61.5 (31.6–86.1) | 46.2 (23.2–70.9) | 30.7 (9.1–61.4) |
PPV | 72.7 (49.8–89.3) | 66.7 (46.7–82.1) | 55.6 (35.3–74.5) | 75.0 (50.9–91.3) | 68.2 (47.3–83.6) | 60.9 (38.5–80.3) |
NPV | 92.9 (66.1–99.8) | 91.7 (64.6–98.5) | 77.8 (40–97.2) | 88.9 (51.8–99.7) | 85.7 (48.7–97.4) | 66.7 (22.3–95.7) |
+LR | 2.9 (1.5–5.8) | 2.2 (1.7–2.9) | 1.4 (1.0–2.1) | 2.4 (1.2–4.9) | 1.7 (1.3–2.3) | 1.3 (0.8–1.9) |
−LR | 0.09 (0.01–0.6) | 0.1 (0.0–0.8) | 0.32 (0.08–1.3) | 0.1 (0.01–0.7) | 0.1 (0.0–1.4) | 0.4 (0.09–1.9) |