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Table 3 Particular settings of Campbell and Steele’s [5] method

From: Approximate parameter inference in systems biology using gradient matching: a comparative evaluation

Abbreviation

Definition

Details

10C

10 chains

When comparing our methods, it was of interest to see how the performance depended on the number of parallel MCMC chains, as originally the authors used 4 chains

Obs20

20 observations

Originally, the authors use 401 observations. We reduced this to a dataset size more usual with these types of experiments to observe the dependency of the methods on the amount of data

15K

15 knots

The method in C&S uses B-splines interpolation. We changed the original tuning parameters from the authors' paper to observe the sensitivity of the parameter estimation by these tuning parameters

P3

polynomial order 3 (cubic spline)

The original polynomial order is 5 and again, we wanted to observe the sensitivity of the parameter estimation by these tuning parameters

  1. Table reproduced from [13], with permission from Springer