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Fig. 4 | BioMedical Engineering OnLine

Fig. 4

From: MRI signal intensity differentiation of brainstem encephalitis induced by Enterovirus 71: a classification approach for acute and convalescence stages

Fig. 4

Different stages histogram plots comparison for T1WI and T2WI individually. a Histograms for T1 signal intensity of three groups. b Histograms for T2 signal intensity of three groups. In practice, the overall T1 signal intensity values increase as we traverse from the acute to the convalescence stages, and then to the healthy subjects. However, exceptions of this can happen in 4 of the cases where the condition deteriorate, the primary lesion in the brainstem that developed in conjunction to encephalomalacia resulting in a lower signal in T1WI and higher signal in T2WI. This produces an outlier represented by an extra secondary peak on the left side of the histogram (lower signal intensity values) in the T1WI, and on right side of the histogram (higher signal intensity values) in the T2WI

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