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Table 2 Evaluation of two sample t tests between 37 NC and 20 AD subjects

From: Construction and comparative evaluation of different activity detection methods in brain FDG-PET

MNI Cluster size (voxels) Max. t-score Voxel (x, y, z) Brain area
CAD4D 24,350 13.04 (−40; −72; 42) Left precuneus, parietal lobe
SPM 23,518 11.88 (−36; −74; 40) Left precuneus, parietal lobe
TAL Cluster size (voxels) Max. t-score Voxel (x, y, z) Brain area
CAD4D(TAL) 13,552 11.93 (−38; −65; 27) Left middle temporal gyrus, temporal lobe
SPM(TAL) 12,980 11.44 (−37; −73; 35) Left precuneus, parietal lobe
NEUROSTAT 14,637 12.85 (−40; −71; 33) Angular gyrus, temporal lobe
  1. Extracted total hypometabolic cluster size at p < 0.001 (as displayed in Fig. 5), maximum t-score with position and corresponding brain area
  2. Upper table: using CAD4D and SPM normalized images in MNI space
  3. Lower table: using CAD4D, SPM and NEUROSTAT normalized images in Talairach space