Figure 1

The results of H&E staining of pathology morphological examination of vascular in sham group and in the balloon injury group. A, B In the sham group, the intima was smooth, the internal elastic lamina was intact (H&E staining × 100), and endothelial cells were visible (H&E staining × 400); (C): 4 days after balloon injury, elastic plate fractures were visible and medial smooth muscle cells migrated to the intima (H&E staining × 400); (D): 7 days after balloon injury, a few of neointimals grew into the lumen (H&E staining × 400); (E): 14 days after balloon injury, hyperplasia of intima was faster and the lumen began to narrow (H&E staining × 100); (F): 14 days after balloon injury, hyperplasia of intima was faster and there were more vascular smooth muscle cells and extracellular matrix in neointimal (H&E staining × 400); (G): 28 days after balloon injury, intimal hyperplasia was significant and lumen reduced significantly (H&E staining × 100); (H): 28 days after balloon injury, there were many vascular smooth muscle cells and extracellular matrix in neointimal (H&E staining × 400).