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Table 1 Transmural isotherm depths and ice volumes for varying interim thawing phase durations

From: Simulation and evaluation of freeze-thaw cryoablation scenarios for the treatment of cardiac arrhythmias

Thaw dur.

1F

1T

2F

(s)

-10°C

-20°C

IV

-10°C

-20°C

IV

-10°C

-20°C

IV

 

(mm)

(mm)

(mm 3 )

(mm)

(mm)

(mm 3 )

(mm)

(mm)

(mm 3 )

0

X

X

X

X

X

X

4.5

3.2

333

5

4.1

3.0

286

3.3

0.6

170

4.4

3.2

326

10

2.5

0.0

94

4.4

3.2

322

15

0.0

0.0

0

4.4

3.2

319

20

4.1

3.0

286

0.0

0.0

0

4.4

3.2

316

  1. Transmural depths of selected isotherms and ice (= tissue below solidus temperature of -10°C) volumes (IV) for ablation protocols with an initial freezing phase of 150 s, an interim thawing duration between 0 s and 20 s, a second freezing phase of 150 s and final rewarming.