Figure 1
From: Effect of 3D-scaffold formation on differentiation and survival in human neural progenitor cells
Interaction of the AFM tip with a PM fibre. (A) Interaction of the AFM tip with a PuraMatrix fibre can be well approximated by the interaction of a sphere (radius R) with a cuboid (width w and height h). The upper scheme shows that the spatial extension of the AFM tip leads to a broadening of the slab width w AFM in the AFM image whereas the cuboid height remains unaffected, i.e. h AFM = h. (B) AFM image (PM 0.15% sample) in 3D view with false colour coding: brighter structures are higher than darker ones. AFM provides us with structural information in three dimensions, which allows us determine the structure of the network formed by these fibres.