Figure 3
From: Numerical optimization of gene electrotransfer into muscle tissue
Geometrical and electrical parameters analyzed in the parametric and optimization study. Two electrodes and six electrodes in muscle tissue in A) the XY plane and B) the XZ plane are shown. The following parameters were optimized: d (4 mm and 8-56 mm, 8 mm step); b (4-28 mm, step of 4 mm); z (10-40 mm; 10 mm step); ϕ (0-90 °; 22.5° steps) and U (400-2400 V, 200 V step for six electrodes; 600-3000 V for two electrodes). Note that ϕ = 0° is referred to in the text as the parallel orientation, while ϕ = 90° is referred to as the perpendicular orientation.