An example of minute-by-minute continuous prediction with HEs. The gap and observation window sizes are 1 and 0.5 hour, respectively. The top plot shows the true and predicted (from regression) MAPs, and the dashed line at 60 mmHg represents the HE threshold. The bottom plot shows the corresponding posterior probabilities of hypotension from the binary classifier. The results from both single and multiple compilation are shown. The periods of no prediction are due to inadequate input data. To facilitate comparison in the top plot, the predicted values were shifted to remove the gap. This implies that the predictions were actually generated 1 hour in advance. However, the bottom plot was not temporally aligned to preserve the predictive nature.