The homeostatic architecture of the bone model, the initial architectures and loading conditions of the seven simulation cases, and their simulation results. a The homeostatic structure of the bone model, which is the initial architecture of simulations 1, 2, 4, 5, 6 and 7. b The initial architecture of simulation 3: two struts were artificially disconnected (inside the two circles), while the external stress was maintained. c The initial architecture and loading condition of simulation 4. The initial structure was the homeostatic structure. The orientation of the applied stress was changed from 30° to 0°. d Result of simulation 1. e Result of simulation 2. f Result of simulation 3. g Result of simulation 4. h Result of simulation 5. i Result of simulation 6. j Result of simulation 7.