A computational model of skeletal muscle metabolism linking cellular adaptations induced by altered loading states to metabolic responses during exercise

Table 2 Arterial species concentrations (mM) and blood-tissue partition coefficients (unitless) estimated from resting conditions for three different loading states.

Species	Arterial Species Concentrations			Blood-Tissue Partition Coefficients
	Sedentary	Loaded	Unloaded	Sedentary	Loaded	Unloaded
GLU	4.2	4.2	4.2	7.62	7.62	7.62
PYR	0.068	0.068	0.068	1.3	1.3	1.3
LAC	0.7	0.7	0.7	0.471	0.471	0.471
ALA	0.192	0.192	0.24	0.182	0.182	0.219
TGL	0.99	0.86	1.26	0.0667	0.0492	0.0679
GLC	0.06	0.06	0.04	1.02	1.02	0.7
FFA	0.59	0.59	0.43	0.867	0.867	0.587
CO2	21.7	21.7	21.7	1.02	1.02	1.02
O2	8.0	8.0	8.0	1.65	1.65	1.65

The species concentrations are obtained from a variety literature sources on skeletal muscle metabolism (for references, see the text in Method section). The partition coefficients σ is calculated from the formula C_b,j = C_v,j = σ_j C_c,j, where C_b,j, C_v,j and C_c,j are the blood, venous and tissue cells species concentrations

ISSN: 1475-925X