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Figure 5 | BioMedical Engineering OnLine

Figure 5

From: A computational model of skeletal muscle metabolism linking cellular adaptations induced by altered loading states to metabolic responses during exercise

Figure 5

Dynamic concentration profiles of phosphocreatine (PCr) and inorganic phosphate (Pi) during a 10-min moderate-intensity exercise period (WR = 65W) of a sedentary individual. The steady state responses are present from time -5 min to time 0 min when the step change in work rate (WR) is initiated. The solid and dashed lines represent the model simulation results with the symbols representing experimental data points [mean ± SD] [65]. The time constants of both [PCr] drop and [Pi] rise are approximately equal (τPCr ≈ τPi ≈ 0.5 min). The dynamics of [PCr] match very well with the dynamics of muscle VO2 [72-74].

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