Table 1B Parameters in MINMOD.
Quantity | Description | Value and Unit | Dimensions | ||
|---|---|---|---|---|---|
M | L | T | |||
p 1 | Insulin-independent glucose disappearance rate. Also known as glucose effectiveness (SG). | ~10-2 min-1 | 0 | 0 | -1 |
p 2 | Rate constant expressing the spontaneous decrease of tissue glucose uptake ability. | ~10-2 min-1 | 0 | 0 | -1 |
p 3 | Insulin-dependent increase in tissue glucose uptake ability, per unit of insulin concentration excess over baseline insulin. | ~10-5 min-2 (μU/ml)-1 | -1 | 3 | -2 |
n | Disappearance rate of endogenous insulin. | ~10-1 min-1 | 0 | 0 | -1 |
γ | Rate of second phase endogenous insulin secretion | ~10-2–10-3 (μU/ml) min-2 | 0 | 0 | -2 |
G b | Baseline plasma glucose | ~100 mg/dl | 1 | -3 | 0 |
G 0 | Initial glucose concentration during FSIVGTT | ~300 mg/dl | 1 | -3 | 0 |
h | A threshold value (higher than basal) for plasma glucose above which the second phase insulin secretion is stimulated | ~100 mg/dl | 1 | -3 | 0 |
l b | Baseline plasma insulin | ~10 μU/ml | 1 | -3 | 0 |
l 0 | Initial insulin concentration | ~30 μU/ml | 1 | -3 | 0 |