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Figure 4 | BioMedical Engineering OnLine

Figure 4

From: Theoretical modeling for radiofrequency ablation: state-of-the-art and challenges for the future

Figure 4

Example of experimental validation of the theoretical models by comparing computed temperature distributions and histologic samples. (a) Temperature distributions in the cornea during RF heating using constant voltage (scale in °C). Top: 16 V after 1 s. Bottom: 21 V after 1 s. (b) Cross-section of corneas heated with an active electrode of 200 μm diameter (hematoxylin and eosin, ×40). Top: 16 V after 1 s. Bottom: 21 V after 1 s. The lesion dimensions (central depth and surface width) were assessed using the coagulation contour, and were expressed as % of cornea thickness. In this case, the 100°C isothermal line was used to compare the experimental and computed results since it had been observed that the coagulation contour occurs in the temperature range around 100°C using short heating times [49].

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