Before Ischemia | After Ischemia | ||||||||
---|---|---|---|---|---|---|---|---|---|
Con | Dbt | Dop | Dig | Lev | Con | Dbt | Dop | Dig | Lev |
Heart Rate (beats per minute) | |||||||||
236 ± 3 | 350 ± 12* | 298 ± 9* | 259 ± 6 | 270 ± 5* | 242 ± 8 | 350 ± 15# | 298 ± 13# | 269 ± 10 | 271 ± 7 |
Systolic LVP (mmHg) | |||||||||
32 ± 1 | 73 ± 5* | 55 ± 3* | 49 ± 2* | 51 ± 2* | 29 ± 2 | 44 ± 3#†| 40 ± 1#†| 37 ± 2#†| 35 ± 2#†|
Diastolic LVP (mmHg) | |||||||||
3 ± 1 | 2 ± 1 | 4 ± 1 | 6 ± 1 | 3 ± 2 | 13 ± 2†| 13 ± 2†| 13 ± 2†| 14 ± 1†| 18 ± 2†|
Phasic (systolic-diastolic) LVP (mmHg) | |||||||||
28 ± 2 | 71 ± 6* | 52 ± 3* | 43 ± 1* | 48 ± 3* | 16 ± 2†| 32 ± 4#†| 27 ± 2#†| 23 ± 2#†| 17 ± 3†|
Systolic [Ca2+] (nM) | |||||||||
258 ± 4 | 609 ± 48* | 307 ± 14* | 301 ± 10* | 367 ± 31* | 381 ± 27†| 544 ± 56# | 310 ± 19# | 333 ± 22 | 369 ± 24 |
Diastolic [Ca2+] (nM) | |||||||||
103 ± 2 | 140 ± 10* | 108 ± 4 | 106 ± 2 | 110 ± 3 | 124 ± 9†| 148 ± 13 | 107 ± 9 | 100 ± 6# | 124 ± 10 |
Phasic (systolic-diastolic) [Ca2+] (nM) | |||||||||
155 ± 5 | 469 ± 72* | 198 ± 12* | 194 ± 10* | 257 ± 32* | 257 ± 19†| 396 ± 53# | 204 ± 20 | 234 ± 17 | 245 ± 23 |