Figure 6
From: Gap-junction channels inhibit transverse propagation in cardiac muscle
Special experiment to test why presence of many gap-junction channels inhibits transverse propagation. Stimulated Cell A1 only. Rol2 of 1.0 MΩ. A: Uniform value for Rgj of 1.0 MΩ (10,000 channels) in all 5 chains. Chains D and E failed to respond. Compare with Fig. 3B for the standard Rol2 of 0.2 MΩ. B: The Rgj values in chains D and E only were changed to infinity (0 channels). Now chains D and E responded. See text for details. This demonstrates that removing the gj-channels in the two chains awaiting excitation (D, E) increased the safety factor for transverse propagation.