Figure 2
From: Gap-junction channels inhibit transverse propagation in cardiac muscle
Blow-up of a small portion of the 5 × 5 model to show the electrical circuit for each basic unit, including the "black-box" required for excitability. Rol2 represents the longitudinal resistance of the interstitial fluid between the parallel chains; the higher the resistance, the tighter the packing of the chains. Depolarizing current (0.25 nA) is applied to the interior of either the first cell or the entire chain (A-chain) simultaneously. When gap-junction channels were added, a resistor (Rgj) was inserted across each cell junction, from the interior of one cell to the interior of the next one.