TY - JOUR AU - Zhong, Liang AU - Ghista, Dhanjoo N. AU - Ng, Eddie YK AU - Lim, Soo T. PY - 2005 DA - 2005/02/11 TI - Passive and active ventricular elastances of the left ventricle JO - BioMedical Engineering OnLine SP - 10 VL - 4 IS - 1 AB - Description of the heart as a pump has been dominated by models based on elastance and compliance. Here, we are presenting a somewhat new concept of time-varying passive and active elastance. The mathematical basis of time-varying elastance of the ventricle is presented. We have defined elastance in terms of the relationship between ventricular pressure and volume, as: dP = EdV + VdE, where E includes passive (Ep) and active (Ea) elastance. By incorporating this concept in left ventricular (LV) models to simulate filling and systolic phases, we have obtained the time-varying expression for Ea and the LV-volume dependent expression for Ep. SN - 1475-925X UR - https://doi.org/10.1186/1475-925X-4-10 DO - 10.1186/1475-925X-4-10 ID - Zhong2005 ER -