Figure 1

Sensitivity of a CDI sequence is proportional to the duration of applied electric pulses t _c multiplied by SNR of the conventional (magnitude) MR image. As the latter is in most sequences exponentially decaying with the relaxation time T₂ the highest sensitivity is obtained at t _c = T₂. The condition is in practice difficult to meet as most biomedical CDI applications require either very short and high-current pulses (electroporation, IRE) or very long and low-current pulses (CDI of physiological currents).