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Table 1 Incidence, prevelance and other statistics for five cardiomyopathies and a more prevalent pediatric congential heart disease called Tetralogy of Fallot or ToF, with associated right ventricular abnormalities.

From: cMRI-BED: A novel informatics framework for cardiac MRI biomarker extraction and discovery applied to pediatric cardiomyopathy classification

CM Subtypes

HCM

DCM

ARVC/D

NCM

RCM & Iron mediated CM

ToF16

Incidence (I) OR Prevalence (P)

P = 1:500 in absence of aortic valve disease or systemic hypertension

I = 5-8 cases /100,000

P = 36 cases /100,000

I = 1/ 10,000

I = 0.05% to 0.24%

I = 11.4% to 15.1% in Thalassemia major patients

Transfusion Dependent

I = 9/1000 live births

#Patients evaluated for CM

46

129

44

31

35

684

Total number of positive diagnosis w/ CMRI CM

11

18

4

15

12

119

cMRI-based QUANTITATIVE markers

LV myocardial wall thickness

ABNL

ABNL

NL

ABNL

ABNL

NL

LV mass index

ABNL

ABNL

NL

ABNL

ABNL

NL

LV Volume index

ABNL

ABNL

NL

ABNL

ABNL

ABNL

RV Volume index

NL

ABNL

ABNL

NL

ABNL

ABNL

cMRI-based QUALITATIVE markers

Myocardial Delayed Enhancement

+/-

+/-

+/-

+/-

+/-

+

Wall motion abnormalities

+/-

+/-

+/-

+/-

+/-

+/-

  1. Some examples of standard quantitative and qualitative markers from cMRI that are associated with observed normal (NL) or abnormal (ABNL) values in each disease based on patients seen at the Children's Hospital of Pittsburgh (CHP) between 2000 and 2013. LV refers to Left Ventricular and RV to Right Ventricular regions. The qualitative variables shown in the table are assigned values of + or - indicating that some patients for the particular subtype indicated presence or absence of that abnormality.