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Table 2 Clinicopathologic characteristics according to 3 molecular subtypes.

From: Identifying molecular subtypes related to clinicopathologic factors in pancreatic cancer

  Subtype 1 (n = 43) Subtype 2 (n = 45) Subtype 3 (n = 8) P-value
Age (mean ± SD) 66.3 ± 8.1 64.2 ± 10.3 64.8 ± 7.4 0.570
Male gender 22 (51.2%) 20 (44.4%) 5 (62.5%) 0.585
Tumor size (cm) 3.0 ± 1.0 3.4 ± 1.1 3.6 ± 0.8 0.073
R status     0.029
  R0 39 (90.7%) 31 (68.9%) 6 (75.0%)  
  R1, R2 4 (9.3%) 14 (31.1%) 2 (25.0%)  
AJCC Stage     0.304
  Stage IIA 19 (44.2%) 21 (46.7%) 1 (12.5%)  
  Stage IIB 21 (48.8%) 22 (48.9%) 7 (87.5%)  
Histologic differentiation     0.417
  Well differentiated 1 (2.3%) 1 (2.2%) 1 (12.5%)  
  Moderately differentiated 39 (90.7%) 38 (84.4%) 7 (87.5%)  
  Poorly differentiated 3 (7.0%) 6 (13.3%) 0  
Perineural invasion 35 (81.4%) 40 (88.9%) 8 (100%) 0.298
Endolymphatic invasion 17 (39.5%) 18 (40.0%) 4 (50.0%) 0.690
Endovenous invasion 9 (20.9%) 16 (35.6%) 0 0.070
Adjuvant chemotherapy 37 (86.0%) 43 (95.6%) 7 (87.5%) 0.215
  Gemcitabine 21 (48.8%) 30 (66.7%) 5 (62.5%) 0.267
  5-FU 10 (23.3%) 10 (22.2%) 1 (12.5%) 0.936
  Unknown 6 (14.0%) 3 (6.7%) 1 (12.5%)  
Recurrence 21 (48.8%) 32 (71.1%) 5 (62.5%) 0.091
  Local 10 (23.3%) 11 (24.4%) 2 (25.0%) 1.0
  Distant 17 (39.5%) 30 (66.7%) 3 (37.5%) 0.022